Larry Smith told the TEDxUW (University of Waterloo) audience that they will fail to have a great career.  After all, there are ever so many excuses that crop up to justify why you can't follow your passion.  Alas, there is no such thing as a "good" career according to Larry, so if you try to settle for one, you'll just end up with one of those terrible, soul-sucking jobs.  Unless...